Anti-Apolipoprotein A I APOA1 Rabbit Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Apolipoprotein A I APOA1 Rabbit Monoclonal Antibody

catalog :

M00717

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

EFB-1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M00717

Product Name :

Anti-Apolipoprotein A I APOA1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

EFB-1

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:5000~1:10000 .IHC 1:50~1:200 .ICC/IF 1:50~1:200 .IP 1:50

Description :

Boster Bio Anti-Apolipoprotein A I APOA1 Rabbit Monoclonal Antibody catalog # M00717. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

APOA1

Uniprot ID :

P02647

Immunogen :

A synthesized peptide derived from human Apolipoprotein A1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

apolipoprotein A1

Synonyms :

Apolipoprotein A-I; Apo-AI; ApoA-I; Apolipoprotein A1; Proapolipoprotein A-I; ProapoA-I; Truncated apolipoprotein A-I; Apolipoprotein A-I (1-242); APOA1

Molecular Weight :

30778 MW

Protein Function :

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

Subcellular Localization :

Secreted.

Tissue Specificity :

Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking. It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.

Research Category :

Cardiovascular, Cholesterol Metabolism, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lipids / Lipoproteins, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Signal Transduction