Anti-Human Emerin DyLight® 550 conjugated EMD Antibody(monoclonal, 5A10)

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Human Emerin DyLight® 550 conjugated EMD Antibody(monoclonal, 5A10)

catalog :

M00714-Dyl550

quantity :

50 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

DyLight 550

reactivity :

human

application :

flow cytometry

product information

SKU :

M00714-Dyl550

Product Name :

Anti-Human Emerin DyLight® 550 conjugated EMD Antibody(monoclonal, 5A10)

Size :

50 ug/vial

Clonality :

Monoclonal

Host :

Mouse

Conjugate :

DyLight®550

Reactivity :

Human

Application(s) :

Flow Cytometry

Application Details :

Flow Cytometry, 1-3μg/1x10^6 cells

Description :

Boster Bio Anti-Human Emerin DyLight® 550 conjugated EMD Antibody (monoclonal, 5A10) catalog # M00714-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

EMD

Uniprot ID :

P50402

Immunogen :

different from the related mouse sequence by eight amino acids, and from the related rat sequence by nine amino acids.
MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIF
EYETQRRRL),
A synthetic peptide corresponding to a sequence at the N-terminus of human Emerin (1-48aa

Form :

Liquid

Contents :

Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.

Cross-reactivity :

No cross reactivity with other proteins.

Isotype :

IgG1

Storage :

At 2-8?C for one year from date of receipt. Protect from light. Do not freeze.

Gene Full Name :

emerin

Synonyms :

Emerin; EMD; EDMD; STA

Protein Function :

Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta- catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.

Subcellular Localization :

Nucleus inner membrane

Tissue Specificity :

Skeletal muscle, heart, colon, testis, ovary and pancreas.

Research Category :

Biochemicals, Chemical Type, Neuroscience, Neurotransmission, Obesity, Receptors / Channels