Anti-Bov CD62L Purified SELL Monoclonal Antibody | Boster M00652 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Bov CD62L Purified SELL Monoclonal Antibody

catalog :

M00652

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

IVA94

The same clone is also sold as:

Exbio: 11-358-C100
Abnova: MAB0988
OriGene: SM3034P
Invitrogen: MA5-44129, MA1-19304

reactivity :

bovine

application :

immunocytochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M00652

Product Name :

Anti-Bov CD62L Purified SELL Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

IVA94

Host :

Mouse

Reactivity :

Cow, Human

Application(s) :

Flow Cytometry, IP, ICC

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Bov CD62L Purified SELL Monoclonal Antibody catalog # M00652. Tested in Flow Cytometry, IP, ICC applications. This antibody reacts with Cow, Human.

Concentration :

1 mg/ml

Gene Name :

SELL

Uniprot ID :

P98131

Immunogen :

Bovine leukocytes.

Form :

Liquid

Contents :

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Purification :

Purified by protein-A affinity chromatography

Isotype :

Mouse IgG1

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

SET domain containing 1A, histone lysine methyltransferase

Synonyms :

Histone-lysine N-methyltransferase SETD1A; Lysine N-methyltransferase 2F; SET domain-containing protein 1A; Hset1a; Set1/Ash2 histone methyltransferase complex subunit SET1; SETD1A; KIAA0339; KMT2F; SET1; SET1A

Protein Function :

Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1B suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression.

Subcellular Localization :

Nucleus speckle. Chromosome.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Background :

Histone-lysine N-methyltransferase SETD1A is an enzyme that in humans is encoded by the SETD1A gene. It is mapped to 16p11.2. The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.