This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-Hu CD62L Purified SELL Monoclonal Antibody
catalog :
M00652-2
quantity :
0.1 mg (C100)
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DREG56

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
product information
SKU :
M00652-2
Product Name :
Anti-Hu CD62L Purified SELL Monoclonal Antibody
Size :
0.1 mg (C100)
Clonality :
Monoclonal
Clone Number :
DREG56
Host :
Mouse
Reactivity :
Human
Application(s) :
Flow Cytometry, IP, WB, IHC
Application Notes :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Description :
Boster Bio Anti-Hu CD62L Purified SELL Monoclonal Antibody catalog # M00652-2. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human.
Concentration :
1 mg/ml
Gene Name :
SELL
Uniprot ID :
P14151
Immunogen :
PMA-activated human peripheral blood leukocytes
Form :
Liquid
Contents :
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification :
Purified by protein-A affinity chromatography
Isotype :
Mouse IgG1
Storage :
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Gene Full Name :
ubiquitin specific peptidase 21
Synonyms :
Ubiquitin carboxyl-terminal hydrolase 21; Deubiquitinating enzyme 21; Ubiquitin thioesterase 21; Ubiquitin-specific-processing protease 21; USP21; USP23; PP1490
Protein Function :
Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination. Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates. Deubiquitinates BAZ2A/TIP5 leading to its stabilization.
Subcellular Localization :
Nucleus. Cytoplasm.
Tissue Specificity :
Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC.
Background :
Ubiquitin carboxyl-terminal hydrolase 21 is a protein that in humans is encoded by the USP21 gene. It is mapped to 1q23.3. This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits