Anti-DKK1 Rabbit Monoclonal Antibody | Boster M00632 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-DKK1 Rabbit Monoclonal Antibody

catalog :

M00632

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

FHG-4

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

product information

SKU :

M00632

Product Name :

Anti-DKK1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

FHG-4

Host :

Rabbit

Reactivity :

Human, Rat

Application(s) :

Flow Cytometry, IF, IHC, ICC, WB

Application Details :

WB 1:1000-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .Flow Cytometry 1:50

Description :

Boster Bio Anti-DKK1 Rabbit Monoclonal Antibody catalog # M00632. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

DKK1

Uniprot ID :

O94907

Immunogen :

A synthesized peptide derived from human DKK1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Dickkopf-related protein 1

Synonyms :

Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK; DKK1; UNQ492/PRO1008;

Molecular Weight :

28672 MW

Protein Function :

Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Subcellular Localization :

Secreted.

Tissue Specificity :

Placenta

Research Category :

Cardiovascular, Developmental Biology, Embryogenesis, Immunology, Secreted, Signaling Pathways, Stem Cells