Anti-SUMO-1 Monoclonal Antibody | Boster M00631 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-SUMO-1 Monoclonal Antibody

catalog :

M00631

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM571

reactivity :

human

application :

immunohistochemistry

product information

sku :

M00631

status :

Enabled

name :

Anti-SUMO-1 Monoclonal Antibody

category name :

Primary Antibodies, Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

SUMO1

price various sizes :

20ug sample size / $99 100ug / $299 100ug+Free HRP Secondary BA1050 / $299 100ug+Free Biotin Secondary BA1001 / $299

clonality :

Monoclonal

clone number :

SPM571

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

description :

Mouse Monoclonal Antibody [Clone SPM571] antibody for SUMO 1/SUMO1 detection. Host: Mouse.Size: 100ug/vial. Tested applications: IF. Reactive species: Human. SUMO 1/SUMO1 information: Molecular Weight: 11557 MW; Subcellular Localization: Nucleus membrane. Nucleus speckle. Cytoplasm. Nucleus, PML body. Cell membrane . Recruited by BCL11A into the nuclear body.

short description :

Anti-SUMO-1 Antibody

size :

100 ug/vial

sample size available :

20ug for $99, contact us for details

uniprot id :

P63165

host :

Mouse

immunogen :

Recombinant human SUMO1 protein

form :

Liquid

application details :

Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT). Immunofluorescence (0.5-1ug/ml)

applications :

IHC

reactivity :

Human

image labels :

Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained withSUMO-1 Monoclonal Antibody (SPM571)

research category :

Cancer, Cardiovascular, Cell Biology, Cell Death, Metabolism, Metabolism Processes, Pathways And Processes, Proteasome / Ubiquitin, Proteolysis / Ubiquitin

synonyms :

Small ubiquitin-related modifier 1;SUMO-1;GAP-modifying protein 1;GMP1;SMT3 homolog 3;Sentrin;Ubiquitin-homology domain protein PIC1;Ubiquitin-like protein SMT3C;Smt3C;Ubiquitin-like protein UBL1;SUMO1;SMT3C, SMT3H3, UBL1;OK/SW-cl.43;

gene full name :

Small ubiquitin-related modifier 1

molecular weight :

11557 MW

protein function :

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Covalently attached to the voltage-gated potassium channel KCNB1; this modulates the gating characteristics of KCNB1 (PubMed:19223394). Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.

subcellular localization :

Nucleus membrane. Nucleus speckle. Cytoplasm. Nucleus, PML body. Cell membrane . Recruited by BCL11A into the nuclear body.

last modified :

2/6/19 22:57