Anti-APE1 Rabbit Monoclonal Antibody | Boster M00627-3 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-APE1 Rabbit Monoclonal Antibody

catalog :

M00627-3

quantity :

100 µl/vial

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

17A44

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

M00627-3

Product Name :

Anti-APE1 Rabbit Monoclonal Antibody

Size :

100 µl/vial

Clonality :

Monoclonal

Clone Number :

17A44

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

WB, IHC

Application Details :

WB 1:1000-1:5000.IHC 1:50-1:200

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-APE1 Rabbit Monoclonal Antibody catalog # M00627-3. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

APEX1

Uniprot ID :

P27695

Immunogen :

A synthesized peptide derived from human APE1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC.

Background :

Factor XI or plasma thromboplastin antecedent is the zymogen form of factor XIa, one of the enzymes of the coagulation cascade. Like many other coagulation factors, it is a serine protease. In humans, Factor XI is encoded by the F11 gene. This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.