Anti-Galectin-3 LGALS3 Monoclonal Antibody | Boster M00621-1 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Galectin-3 LGALS3 Monoclonal Antibody

catalog :

M00621-1

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

monoclonal

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

M00621-1

Product Name :

Anti-Galectin-3 LGALS3 Monoclonal Antibody

Size :

100 ul

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Rat, Mouse

Application(s) :

IF, IHC, WB

Application Details :

WB:1:2,000. IF/ICC and IHC: 1:1,000

Description :

Boster Bio Anti-Galectin-3 LGALS3 Monoclonal Antibody catalog # M00621-1. Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

LGALS3

Uniprot ID :

P17931

Immunogen :

Full length recombinant Galectin-3 expressed in and purified from E. coli

Contents :

Purified antibody at 1mg/mL in 50% PBS, 50% glycerol plus 5mM NaN 3

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Galectin-3

Synonyms :

Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen; LGALS3; MAC2;

Molecular Weight :

26152 MW

Protein Function :

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

Subcellular Localization :

Cytoplasm. Nucleus. Secreted. Secreted by a non-classical secretory pathway and associates with the cell surface.

Tissue Specificity :

A major expression is found in the colonic epithelium. It is also abundant in the activated macrophages. Expressed in fetal membranes.

Research Category :

Cancer, Cell Cycle, Cell Division, Oncoproteins, Tumor Biomarkers