Anti-CD68 (Macrophage Marker) Monoclonal Antibody | Boster M00602 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD68 (Macrophage Marker) Monoclonal Antibody

catalog :

M00602

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

SPM130

The same clone is also sold as:

Santa Cruz Biotechnology: sc-52998
Abnova: MAB12032
Novus Biologicals: NBP2-32831-0.1mg, NBP2-44540, NBP2-34736-0.1mg
OriGene: AM50195PU-T, AM50195PU-S

reactivity :

human

application :

immunohistochemistry, immunocytochemistry

product information

SKU :

M00602

Product Name :

Anti-CD68 (Macrophage Marker) Monoclonal Antibody

Size :

100 ug/vial

Clonality :

Monoclonal

Clone Number :

SPM130

Host :

Mouse

Reactivity :

Human, Monkey, Rabbit

Application(s) :

IF, IHC

Application Details :

Immunohistology (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT).Immunofluorescence (0.5-1ug/ml)

Description :

Boster Bio Anti-CD68 (Macrophage Marker) Monoclonal Antibody catalog # M00602. Tested in IF, IHC applications. This antibody reacts with Human, Monkey, Rabbit.

Gene Name :

CD68

Uniprot ID :

P34810

Immunogen :

Subcellular fraction of human alveolar macrophages

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Purification :

Protein A/G

Isotype :

IgG1, kappa

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Macrosialin

Synonyms :

Macrosialin; Gp110; CD68; CD68;

Molecular Weight :

37408 MW

Protein Function :

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Subcellular Localization :

Isoform Short: Cell membrane; Single-pass type I membrane protein.

Tissue Specificity :

Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.

Research Category :

Cell Type Markers, Immunology