Anti-CD68/Sr D1 Rabbit Monoclonal Antibody | Boster M00602-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD68/Sr D1 Rabbit Monoclonal Antibody

catalog :

M00602-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

GBE-3

reactivity :

human, mouse, rat

application :

western blot

product information

SKU :

M00602-1

Product Name :

Anti-CD68/Sr D1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

GBE-3

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Application Details :

WB 1:500-1:1000

Description :

Boster Bio Anti-CD68/Sr D1 Rabbit Monoclonal Antibody catalog # M00602-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CD68

Uniprot ID :

P34810

Immunogen :

A synthesized peptide derived from human CD68

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Macrosialin

Synonyms :

Macrosialin; Gp110; CD68; CD68;

Molecular Weight :

37408 MW

Protein Function :

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.

Subcellular Localization :

Isoform Short: Cell membrane; Single-pass type I membrane protein.

Tissue Specificity :

Highly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.

Research Category :

Cell Type Markers, Immunology