Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody

catalog :

M00595

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

HEE-8

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

product information

SKU :

M00595

Product Name :

Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

HEE-8

Host :

Rabbit

Reactivity :

Human

Application(s) :

IP, IF, IHC, ICC, WB

Application Details :

WB 1:5000-1:20000 .IHC 1:50-1:200 .ICC/IF 1:100-1:500 .IP 1:50

Description :

Boster Bio Anti-HDAC6/Histone Deacetylase 6 Rabbit Monoclonal Antibody catalog # M00595. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

HDAC6

Uniprot ID :

Q9UBN7

Immunogen :

A synthesized peptide derived from human HDAC6

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Histone deacetylase 6

Synonyms :

Histone deacetylase 6; HD6; 3.5.1.98; HDAC6; KIAA0901; JM21;

Molecular Weight :

131419 MW

Protein Function :

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Subcellular Localization :

Nucleus. Cytoplasm. Perikaryon. Cell projection, dendrite. Cell projection, axon. It is mainly cytoplasmic, where it is associated with microtubules.

Research Category :

Acetylation, Chromatin Modifying Enzymes, Epigenetics and Nuclear Signaling, Signaling Pathways, Stem Cells