Anti-Transferrin Receptor (CD71) TFRC Rabbit Monoclonal Antibody

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Transferrin Receptor (CD71) TFRC Rabbit Monoclonal Antibody

catalog :

M00591-1

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

AOAA-20

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M00591-1

Product Name :

Anti-Transferrin Receptor (CD71) TFRC Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

AOAA-20

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Flow Cytometry, IP, IHC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .IP 1:50 .Flow Cytometry 1:50

Description :

Boster Bio Anti-Transferrin Receptor (CD71) TFRC Rabbit Monoclonal Antibody catalog # M00591-1. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

TFRC

Uniprot ID :

P02786

Immunogen :

A synthesized peptide derived from human TFR

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Transferrin receptor protein 1

Synonyms :

Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD71; Transferrin receptor protein 1, serum form; sTfR; TFRC;

Molecular Weight :

84871 MW

Protein Function :

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

Subcellular Localization :

Cell membrane ; Single-pass type II membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Research Category :

Pathways And Processes, Response To Hypoxia, Serum Proteins, Stem Cells, Surface Molecules, T Lymphocytic Lineage