Anti-Clusterin Purified Monoclonal Antibody | Boster M00590-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Clusterin Purified Monoclonal Antibody

catalog :

M00590-1

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HS-3

The same clone is also sold as:

Exbio: 11-421-C100, 11-421-C025
Invitrogen: MA1-19385
Abnova: MAB12529
Santa Cruz Biotechnology: sc-51579
Novus Biologicals: NB500-552-0.1mg
OriGene: DM2012, AM03078PU-N

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

M00590-1

Product Name :

Anti-Clusterin Purified Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

Hs-3

Host :

Mouse

Reactivity :

Human

Application(s) :

WB, IHC, ICC, ELISA

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Clusterin Purified Monoclonal Antibody catalog # M00590-1. Tested in ELISA, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

CLU

Uniprot ID :

P10909

Immunogen :

Freshly ejaculated human sperms were washed in PBS and extracted in 3% acetic acid, 10% glycerol, 30 mM benzaminidine. The acid extract was dialyzed against 0.2% acetic acid and subsequently used for immunization.

Form :

Liquid

Contents :

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Purification :

Purified by protein-A affinity chromatography

Isotype :

Mouse IgG1

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

sprouty RTK signaling antagonist 2

Synonyms :

Protein sprouty homolog 2; Spry-2; SPRY2

Protein Function :

May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis.

Subcellular Localization :

Ruffle membrane. Cytoskeleton.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

Sprouty homolog 2 (Drosophila), also known as SPRY2, is a protein which in humans is encoded by the SPRY2 gene. It is mapped to 13q31.1. This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.