Anti-TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody

catalog :

M00477

quantity :

100 ug/vial

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

polyclonal

reactivity :

human

application :

immunohistochemistry

product information

SKU :

M00477

Product Name :

Anti-TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody

Size :

100 ug/vial

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Equine, Canine, Bovine, Rat, Mouse, Human

Application(s) :

IHC

Application Details :

Immunohistology (Formalin-fixed) (1-2ug/ml for 30 minutes at RT).Immunofluorescence (1-2ug/ml)

Description :

Boster Bio Anti-TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody catalog # M00477. Tested in IHC applications. This antibody reacts with Bovine, Canine, Equine, Human, Mouse, Rat.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

TIMP3

Uniprot ID :

P35625

Immunogen :

The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in mouse and rat.

Form :

Liquid

Contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Purification :

protein A

Isotype :

IgG

Storage :

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Gene Full Name :

Metalloproteinase inhibitor 3

Synonyms :

Metalloproteinase inhibitor 3; Protein MIG-5; Tissue inhibitor of metalloproteinases 3; TIMP-3; TIMP3;

Molecular Weight :

24145 MW

Protein Function :

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

Subcellular Localization :

Secreted, extracellular space, extracellular matrix.

Research Category :

Angiogenesis, Apoptosis, Cancer, Cardiovascular, Cell Biology, Cytoskeleton / Ecm, Ecm Enzymes, Extracellular Matrix, Invasion/Microenvironment, Neuroscience, Protease Inhibitors, Proteolysis / Ubiquitin, Sensory System, Signal Transduction, Visual System