Anti-MIF Rabbit Monoclonal Antibody | Boster M00411 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-MIF Rabbit Monoclonal Antibody

catalog :

M00411

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

ABAG-13

The same clone is also sold as:

MyBioSource: MBS179316

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

product information

SKU :

M00411

Product Name :

Anti-MIF Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

ABAG-13

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Application(s) :

Flow Cytometry, IP, WB

Application Details :

WB 1:500-1:2000 .IP 1:50 .Flow Cytometry 1:50

Description :

Boster Bio Anti-MIF Rabbit Monoclonal Antibody catalog # M00411. Tested in Flow Cytometry, IP, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

MIF

Uniprot ID :

P14174

Immunogen :

A synthesized peptide derived from human MIF

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Macrophage migration inhibitory factor

Synonyms :

Macrophage migration inhibitory factor; MIF; 5.3.2.1; Glycosylation-inhibiting factor; GIF; L-dopachrome isomerase; L-dopachrome tautomerase; 5.3.3.12; Phenylpyruvate tautomerase; MIF; GLIF, MMIF;

Molecular Weight :

12476 MW

Protein Function :

Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

Subcellular Localization :

Secreted. Cytoplasm. Does not have a cleavable signal sequence and is secreted via a specialized, non- classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.

Research Category :

Immunology, Innate Immunity, Macrophage / Inflamm.