Anti-Hu CD47 Purified Monoclonal Antibody | Boster M00360-1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hu CD47 Purified Monoclonal Antibody

catalog :

M00360-1

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MEM-122

The same clone is also sold as:

OriGene: SM3026P
Invitrogen: MA1-19117, MA1-10239
Exbio: PB-225-T025, 11-225-C100, 1F-225-T100, 1F-225-T025, 11-225-C025, PB-225-T100
Abnova: MAB3839

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry

product information

SKU :

M00360-1

Product Name :

Anti-Hu CD47 Purified Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

MEM-122

Host :

Mouse

Reactivity :

Monkey, Human, Pig

Application(s) :

Flow Cytometry, WB, IHC

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Hu CD47 Purified Monoclonal Antibody catalog # M00360-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey, Pig.

Concentration :

1 mg/ml

Gene Name :

CD47

Uniprot ID :

Q08722

Immunogen :

COS-7 (African green monkey) cells

Form :

Liquid

Contents :

Tris buffered saline (TBS) solution with 15 mM sodium azide

Purification :

Purified by precipitation and chromatography

Isotype :

Mouse IgM

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

RNA binding protein, mRNA processing factor

Synonyms :

RNA-binding protein with multiple splicing; RBP-MS; Heart and RRM expressed sequence; Hermes; RBPMS; HERMES

Protein Function :

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly (A) RNA.

Subcellular Localization :

Nucleus. Cytoplasm. P-body.

Tissue Specificity :

Ubiquitously expressed, at various levels depending on the isoform and the tissue.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Background :

RNA-binding protein with multiple splicing is a protein that in humans is encoded by the RBPMS gene. It is mapped to 8p12. This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms.