Anti-Bmi1 Rabbit Monoclonal Antibody | Boster M00313 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Bmi1 Rabbit Monoclonal Antibody

catalog :

M00313

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

IHE-2

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

M00313

Product Name :

Anti-Bmi1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

IHE-2

Host :

Rabbit

Reactivity :

Human, Rat

Application(s) :

IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200

Description :

Boster Bio Anti-Bmi1 Rabbit Monoclonal Antibody catalog # M00313. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

BMI1

Uniprot ID :

P35226

Immunogen :

A synthesized peptide derived from human Bmi1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Polycomb complex protein BMI-1

Synonyms :

Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; BMI1; PCGF4, RNF51;

Molecular Weight :

36949 MW

Protein Function :

Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.

Subcellular Localization :

Nucleus. Cytoplasm.

Research Category :

Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Differentiation, ChIP’ing Antibodies, Chromatin Remodeling, Epigenetics and Nuclear Signaling, Hematopoietic Progenitors, Oncoproteins, Oncoproteins/Suppressors, Proto-Oncogenes, Stem Cells, Transcription