Anti-Hu CD120a Purified TNFRSF1A Monoclonal Antibody | Boster M00294 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Hu CD120a Purified TNFRSF1A Monoclonal Antibody

catalog :

M00294

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

H398

The same clone is also sold as:

Invitrogen: MA5-49122, BMS106, MA5-28600, MA5-49123, 33-0100
Santa Cruz Biotechnology: sc-52739
Beckman Coulter: A22359
OriGene: SM1185B, SM1185P, SM1185LE, SM1185AF, TA700021
Abcam: ab194814
Bio-Rad: MCA1340, MCA1340T
MyBioSource: MBS214946
Exbio: 11-773-C025, 11-773-C100, 1P-773-T100, 12-773-C100

reactivity :

human

application :

immunohistochemistry, immunoprecipitation, flow cytometry

product information

SKU :

M00294

Product Name :

Anti-Hu CD120a Purified TNFRSF1A Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

H398

Host :

Mouse

Reactivity :

Human

Application(s) :

Flow Cytometry, IP, IHC

Description :

Boster Bio Anti-Hu CD120a Purified TNFRSF1A Monoclonal Antibody catalog # M00294. Tested in Flow Cytometry, IP, IHC applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

TNFRSF1A

Uniprot ID :

P19438

Immunogen :

Recombinant full length human CD120a

Form :

Liquid

Contents :

Phosphate buffered saline (PBS) solution with 15 mM sodium azide

Purification :

Purified by protein-A affinity chromatography

Isotype :

Mouse IgG2a

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

TNF receptor-associated factor 6

Synonyms :

TNF receptor-associated factor 6; 2.3.2.27; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85; RING-type E3 ubiquitin transferase TRAF6 ; TRAF6; RNF85;

Protein Name :

TNF receptor-associated factor 6

Molecular Weight :

59573 MW

Protein Function :

E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c- Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production.

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.