Anti-MITF Antibody (Monoclonal, ABM1H91) | Boster M00269 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-MITF Antibody (Monoclonal, ABM1H91)

catalog :

M00269

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

ABM1H91

reactivity :

human, mouse

application :

western blot, immunohistochemistry

product information

sku :

M00269

status :

Enabled

name :

Anti-MITF Antibody (Monoclonal, ABM1H91)

category name :

Primary Antibodies, Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

MITF

price various sizes :

25ug sample size / $99 100 ug / $299 100 ug+Free HRP Secondary BA1050 / $299 100 ug+Free Biotin Secondary BA1001 / $299

clonality :

Monoclonal

clone number :

ABM1H91

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide.

description :

Monoclonal clone# G2 antibody for MITF detection. Host: Mouse.Size: 100 ug. Tested applications: IHC. Reactive species: Human. MITF information: Molecular Weight: 58795 MW; Subcellular Localization: Nucleus; Tissue Specificity: Isoform M is exclusively expressed in melanocytes and melanoma cells. Isoform A and isoform H are widely expressed in many cell types including melanocytes and retinal pigment epithelium (RPE). Isoform C is expressed in many cell types including RPE but not in melanocyte-lineage cells. Isoform Mdel is widely expressed in melanocytes, melanoma cell lines and tissues, but almost undetectable in non-melanoma cell lines.

short description :

Mouse IgG1 Kappa Monoclonal antibody for MITF detection. Tested with IHC, WB in Mouse, Human.

size :

100 ug

sample size available :

25ug for $99, contact us for details

uniprot id :

O75030

host :

Mouse

immunogen :

A partial length recombinant MITF protein (amino acids 150-427).

form :

Liquid

storage :

Store the antibody at 4 C, stable for 6 months. For long-term storage, store at -20 C. Avoid repeated freeze and thaw cycles.

isotype :

IgG1 Kappa

application details :

Western blot analysis, 2-4 ug/ml. Immunohistochemical analysis, 10 ug/ml.

applications :

IHC, WB

reactivity :

Human, Mouse

image labels :

2 Immunohistochemical analysis of MITF in human Skin tissue using MITF antibody (Clone: ABM1H91) at 10 ug/ml. Western blot analysis of MITF. Anti- MITF antibody (Clone: ABM1H91) was tested at 4 ug/ml on mouse Brain lysate.

competitor equivalent skus :

sc 56433 sc 56725 sc 10999 sc 25386 sc 56726 sc 11002 sc 71587 sc 71588 sc 52938 sc 10999 X sc 25386 X sc 11002 X

research category :

Chip'Ing Antibodies, Domain Families, Epigenetics And Nuclear Signaling, Hlh / Leucine Zipper, Immunology, Innate Immunity, Transcription

synonyms :

Microphthalmia-associated transcription factor;Class E basic helix-loop-helix protein 32;bHLHe32;MITF;BHLHE32;

gene full name :

Microphthalmia-associated transcription factor

molecular weight :

58795 MW

protein function :

Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'- CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest- derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

subcellular localization :

Nucleus.

tissue specificity :

Isoform M is exclusively expressed in melanocytes and melanoma cells. Isoform A and isoform H are widely expressed in many cell types including melanocytes and retinal pigment epithelium (RPE). Isoform C is expressed in many cell types including RPE but not in melanocyte-lineage cells. Isoform Mdel is widely expressed in melanocytes, melanoma cell lines and tissues, but almost undetectable in non-melanoma cell lines.

protein name :

Microphthalmia-associated transcription factor

last modified :

2/6/19 22:57