This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-Hu CD147 Purified BSG Monoclonal Antibody
catalog :
M00248
quantity :
0.1 mg (C100)
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MEM-M6/1

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
product information
SKU :
M00248
Product Name :
Anti-Hu CD147 Purified BSG Monoclonal Antibody
Size :
0.1 mg (C100)
Clonality :
Monoclonal
Clone Number :
MEM-M6/1
Host :
Mouse
Reactivity :
Human
Application(s) :
Flow Cytometry, IP, WB, IHC
Application Notes :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Description :
Boster Bio Anti-Hu CD147 Purified BSG Monoclonal Antibody catalog # M00248. Tested in Flow Cytometry, IP, IHC, WB applications. This antibody reacts with Human.
Concentration :
1 mg/ml
Gene Name :
BSG
Uniprot ID :
P35613
Immunogen :
Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimer).
Form :
Liquid
Contents :
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification :
Purified by protein-A affinity chromatography
Isotype :
Mouse IgG1
Storage :
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Gene Full Name :
selectin, platelet (p-selectin) ligand
Synonyms :
P-selectin glycoprotein ligand 1; PSGL-1; Selectin P ligand; CD162; Selplg; Selp1; Selpl
Protein Function :
A SLe (x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.
Subcellular Localization :
Cell membrane. Single-pass membrane protein.
Tissue Specificity :
Highly expressed in blood, bone marrow, brain, adipose tissue, spleen, and thymus. Also expressed in heart, kidney, liver, muscle, ovary, and stomach.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
Background :
Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162), is a human gene. It is mapped to 5 F; 5 55.59 cM. This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits