Anti-CD147/Emmprin Antibody Picoband™ (monoclonal, 3B13G7)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD147/Emmprin Antibody Picoband™ (monoclonal, 3B13G7)

catalog :

M00248-4

quantity :

100 µg/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B13G7

reactivity :

human

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

product information

SKU :

M00248-4

Product Name :

Anti-CD147/Emmprin Antibody Picoband™ (monoclonal, 3B13G7)

Size :

100 µg/vial

Clonality :

Monoclonal

Clone Number :

3B13G7

Host :

Mouse

Reactivity :

Human, Mouse

Application(s) :

WB, IHC-P, IF

Application Details :

Western blot, 0.25-0.5 µg/ml, Human. Immunohistochemistry(Paraffin-embedded Section), 2-5 µg/ml, Human, Mouse. Immunocytochemistry, 5 µg/ml, Human.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-CD147/Emmprin Antibody Picoband™ (monoclonal, 3B13G7) catalog # M00248-4. Tested in IF, IHC-P, WB applications. This antibody reacts with Human, Mouse.

Concentration :

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Gene Name :

BSG

Uniprot ID :

P35613

Immunogen :

E.coli-derived human CD147/Emmprin recombinant protein (Position: E138-A323). Human CD147/Emmprin shares 51.1% and 51.9% amino acid (aa) sequence identity with mouse and rat CD147/Emmprin, respectively.

Form :

Lyophilized

Contents :

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification :

Immunogen affinity purified.

Isotype :

IgG1

Storage :

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Reconstitution :

Adding 0.2 ml of distilled water will yield a concentration of 500 µg/ml.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.