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product summary
company name :
Boster
product type :
antibody
product name :
Anti-CD86/B7 2 Rabbit Monoclonal Antibody
catalog :
M00220-1
quantity :
100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
BFF-3
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
product information
SKU :
M00220-1
Product Name :
Anti-CD86/B7 2 Rabbit Monoclonal Antibody
Size :
100 µl
Clonality :
Monoclonal
Clone Number :
BFF-3
Host :
Rabbit
Reactivity :
Human, Rat
Application(s) :
Flow Cytometry, IP, IF, IHC, ICC, WB
Application Details :
WB 1:1000-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:50 .Flow Cytometry 1:50 .
Description :
Boster Bio Anti-CD86/B7 2 Rabbit Monoclonal Antibody catalog # M00220-1. Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat.
Concentration :
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Gene Name :
CD86
Uniprot ID :
P42081
Immunogen :
A synthesized peptide derived from human CD86
Form :
Liquid
Contents :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification :
Affinity-chromatography
Storage :
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name :
T-lymphocyte activation antigen CD86
Synonyms :
T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD86; CD86; CD28LG2;
Molecular Weight :
37682 MW
Protein Function :
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Subcellular Localization :
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity :
Expressed by activated B-lymphocytes and monocytes.
Research Category :
Adaptive Immunity, Cell Type Markers, Hematopoietic Progenitors, Host Virus Interaction, Immunology, Interspecies Interaction, Lymphoid, Microbiology, Myeloid, Stem Cells, T Cells
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
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