Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody

catalog :

M00199

quantity :

100 ug/vial

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

WT1/857 + 6F-H2

reactivity :

human, mouse

application :

immunohistochemistry

product information

sku :

M00199

status :

Enabled

name :

Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody

category name :

Primary Antibodies, Monoclonal Antibodies, IHC ICC IF Antibodies

gene name :

WT1

price various sizes :

20ug sample size / $99 100ug / $299 100ug+Free HRP Secondary BA1050 / $299 100ug+Free Biotin Secondary BA1001 / $299

clonality :

Monoclonal

clone number :

WT1/857 + 6F-H2

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

description :

Mouse Monoclonal Antibody [Clone WT1/857 + 6F-H2] antibody for WT1 detection. Host: Mouse.Size: 100ug/vial. Tested applications: IF. Reactive species: Human. WT1 information: Molecular Weight: 49188 MW; Subcellular Localization: Nucleus. Nucleus, nucleolus. Cytoplasm . Shuttles between nucleus and cytoplasm; Tissue Specificity: Expressed in the kidney and a subset of hematopoietic cells.

short description :

Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Antibody

size :

100 ug/vial

sample size available :

20ug for $99, contact us for details

uniprot id :

P19544

host :

Mouse

immunogen :

Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2)

form :

Liquid

application details :

Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT),Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes). Immunofluorescence (0.5-1ug/ml)

applications :

IHC

reactivity :

Human, Mouse

image labels :

Formalin-fixed, paraffin-embedded Human Fetal Kidney stained withWT1 Monoclonal Antibody (WT1/857 + 6F-H2).

competitor equivalent skus :

sc 15421 sc 68880 sc 7385 sc 192 sc 393498 sc 68880 X sc 7385 X sc 192 X

research category :

Cell Adhesion, Cell Type Markers, Cytoskeleton / Ecm, Hematopoietic Progenitors, Immunology, Integrins, Lymphoid, Myeloid, Signal Transduction, Stem Cells, T Lymphocytic Lineage

synonyms :

Wilms tumor protein;WT33;WT1;

gene full name :

Wilms tumor protein

molecular weight :

49188 MW

protein function :

Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.

subcellular localization :

Nucleus. Nucleus, nucleolus. Cytoplasm . Shuttles between nucleus and cytoplasm.

tissue specificity :

Expressed in the kidney and a subset of hematopoietic cells.

last modified :

2/6/19 22:57