This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Boster
product type :
antibody
product name :
Anti-Ms CD80 Purified Monoclonal Antibody
catalog :
M00196-2
quantity :
0.1 mg (C100)
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
16-10A1

The same clone is also sold as:
reactivity :
mouse, dogs
application :
immunohistochemistry, immunoprecipitation, flow cytometry
product information
SKU :
M00196-2
Product Name :
Anti-Ms CD80 Purified Monoclonal Antibody
Size :
0.1 mg (C100)
Clonality :
Monoclonal
Clone Number :
16-10A1
Host :
Hamster
Reactivity :
Mouse, Canine
Application(s) :
Flow Cytometry, IP, IHC
Application Notes :
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Description :
Boster Bio Anti-Ms CD80 Purified Monoclonal Antibody catalog # M00196-2. Tested in Flow Cytometry, IP, IHC applications. This antibody reacts with Canine, Mouse.
Concentration :
1 mg/ml
Gene Name :
Cd80
Uniprot ID :
Q00609
Immunogen :
CD80-transfected CHO cell line
Form :
Liquid
Contents :
Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Purification :
Purified by protein-A affinity chromatography
Isotype :
Armenian Hamster IgG2
Storage :
Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Gene Full Name :
U2 small nuclear RNA auxiliary factor 2
Synonyms :
Splicing factor U2AF 65 kDa subunit; U2 auxiliary factor 65 kDa subunit; hU2AF (65); Hu2af65; U2 snRNP auxiliary factor large subunit; U2AF2; U2AF65
Protein Function :
Plays a role in pre-mRNA splicing and 3'-end processing. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing. Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10. Positively regulates pre-mRNA 3'-end processing by recruiting the CFIm complex to cleavage and polyadenylation signals.
Subcellular Localization :
Nucleus.
Recommended Detection Systems :
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.
Background :
Splicing factor U2AF 65 kDa subunit is a protein that in humans is encoded by the U2AF2 gene. It is mapped to 19q13.42. U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com
925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits