Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody | Boster M00179 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody

catalog :

M00179

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

GE-3

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry

product information

SKU :

M00179

Product Name :

Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

GE-3

Host :

Rabbit

Reactivity :

Human

Application(s) :

IF, IHC, ICC, WB

Application Details :

WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200

Description :

Boster Bio Anti-Caveolin-1 CAV1 Rabbit Monoclonal Antibody catalog # M00179. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CAV1

Uniprot ID :

Q03135

Immunogen :

A synthesized peptide derived from human Caveolin-1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Caveolin-1

Synonyms :

Caveolin-1; CAV1; CAV;

Molecular Weight :

20472 MW

Protein Function :

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Subcellular Localization :

Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae.

Tissue Specificity :

Expressed in muscle and lung, less so in liver, brain and kidney.

Research Category :

Calcium Channels, Calcium Signaling, Cancer, Cancer Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Neuroscience, Neurotransmission, Pathways And Processes, Signal Transduction, Signaling Pathway