Anti-PD-1 Pdcd1 Monoclonal Antibody [7A11B1] | Boster M00178-3 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-PD-1 Pdcd1 Monoclonal Antibody [7A11B1]

catalog :

M00178-3

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7A11B1

The same clone is also sold as:

Abnova: MAB8088
Novus Biologicals: NBP1-75518
Rockland Immunochemicals: 200-301-DK3
Invitrogen: MA5-15780

reactivity :

mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

M00178-3

Product Name :

Anti-PD-1 Pdcd1 Monoclonal Antibody [7A11B1]

Size :

0.1 mg

Clonality :

Monoclonal

Clone Number :

7A11B1

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Application(s) :

ELISA, WB, IHC, IF

Application Details :

PD-1 antibody can be used for detection of PD-1 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL. Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-PD-1 Pdcd1 Monoclonal Antibody [7A11B1] catalog # M00178-3. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Concentration :

1 mg/mL

Gene Name :

Pdcd1

Uniprot ID :

Q02242

Immunogen :

A ~150 amino acid recombinant protein from near the amino terminus of mouse PD-1.

Form :

Liquid

Contents :

PD-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

Purification :

PD-1 Monoclonal Antibody is Protein A purified.

Isotype :

IgG1

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

musashi RNA binding protein 1

Synonyms :

RNA-binding protein Musashi homolog 1; Musashi-1; MSI1

Protein Function :

RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U1-3AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.

Subcellular Localization :

Nucleus. Cytoplasm.

Tissue Specificity :

Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.

Background :

RNA-binding protein Musashi homolog 1 is a protein that in humans is encoded by the MSI1 gene. This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.