Anti-CD11B (L1) monoclonal ITGAM Antibody | Boster M00144-3 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD11B (L1) monoclonal ITGAM Antibody

catalog :

M00144-3

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

product information

SKU :

M00144-3

Product Name :

Anti-CD11B (L1) monoclonal ITGAM Antibody

Size :

100 ul

Clonality :

Monoclonal

Host :

Mouse

Reactivity :

Human, Mouse, Rat

Application(s) :

Application Details :

WB: 1:500~1:1000

Description :

Boster Bio Anti-CD11B (L1) monoclonal ITGAM Antibody catalog # M00144-3. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Gene Name :

ITGAM

Uniprot ID :

P11215

Form :

Liquid

Contents :

1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification :

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Cyclic AMP-dependent transcription factor ATF-6 alpha

Synonyms :

Cyclic AMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 alpha; Activating transcription factor 6 alpha; ATF6-alpha; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; ATF6;

Protein Name :

Cyclic AMP-dependent transcription factor ATF-6 alpha

Molecular Weight :

74585 MW

Protein Function :

Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5'-CCAC[GA]-3'half of the ER stress response element (ERSE) (5'-CCAAT-N (9)-CCAC[GA]-3') and of ERSE II (5'- ATTGG-N-CCACG-3'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.

Subcellular Localization :

Endoplasmic reticulum membrane; Single-pass type II membrane protein.

Tissue Specificity :

Ubiquitous.