antibody

Anti-PDL1 CD274 Monoclonal Antibody [6H10]

M00109-3

0.1 mg

monoclonal

mouse

nonconjugated

6H10

The same clone is also sold as:

• OriGene: TA355068

western blot, ELISA, immunohistochemistry, immunocytochemistry

Anti-PDL1 CD274 Monoclonal Antibody [6H10]

0.1 mg

Monoclonal

6H10

Mouse

Human, Mouse

ELISA, WB, IHC, ICC, IF

WB: 0.25 - 4 µg/mL; IF: 2 µg/mL; IHC-P: 5 µg/mL; ICC: 1 µg/mL. Antibody validated: Western Blot in human and mouse samples; Immunohistochemistry, Immunocytochemistry and Immunofluorescence in human samples. All other applications and species not yet tested.

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Boster Bio Anti-PDL1 CD274 Monoclonal Antibody [6H10] catalog # M00109-3. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse.

1 mg/mL

CD274

Q9NZQ7

Anti-PD-L1 antibody was raised against the extracellular domain of human PD-L1.

Liquid

PD-L1 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.

PD-L1 Antibody is supplied as protein A purified IgG1.

IgG1

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

nerve growth factor receptor

Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor P75ntr; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD271; NGFR; TNFRSF16

Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that binds the precursor forms of NGF, BDNF and NTF3 with high affinity, and has much lower affinity for mature NGF and BDNF. Plays an important role in differentiation and survival of specific neuronal populations during development. Can mediate cell survival as well as cell death of neural cells. Plays a role in the inactivation of RHOA. Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCmgetaN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Cell membrane. Single-pass type I membrane protein. Perikaryon. Growth cone. Dendritic spine.

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for ICC.

The low-affinity nerve growth factor receptor (nerve growth factor receptor (TNFR superfamily, member 16), also called the LNGFR or p75 neurotrophin receptor) is one of the two receptor types for the neurotrophins, a family of protein growth factors that stimulate neuronal cells to survive and differentiate. LNGFR is a member of the tumor necrosis factor receptor (TNF receptor)superfamily indeed, LNGFR was the first member of this large family of receptors to be characterized. It is mapped to 17q21.33. Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.