Anti-Transferrin Purified Azide Free TF Monoclonal Antibody

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Transferrin Purified Azide Free TF Monoclonal Antibody

catalog :

M00094-1

quantity :

0.1 mg (C100)

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HTF-14

The same clone is also sold as:

Bio-Rad: 9100-1055
Novus Biologicals: NBP2-37718, NB500-418
Abcam: ab769
Exbio: 12-258-C100, 11-258-C100, 10-258-C025, 11-258-C025, 10-258-C100
OriGene: BM745S, BM745
Invitrogen: MA1-19013, MA5-44060

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

M00094-1

Product Name :

Anti-Transferrin Purified Azide Free TF Monoclonal Antibody

Size :

0.1 mg (C100)

Clonality :

Monoclonal

Clone Number :

HTF-14

Host :

Mouse

Reactivity :

Human, Pig, Rabbit

Application(s) :

WB, IHC, ICC, ELISA

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-Transferrin Purified Azide Free TF Monoclonal Antibody catalog # M00094-1. Tested in ELISA, IHC, ICC, WB applications. This antibody reacts with Human, Pig, Rabbit.

Concentration :

1 mg/ml

Gene Name :

Uniprot ID :

P02787

Immunogen :

Purified porcine transferrin.

Form :

Liquid

Contents :

Azide free phosphate buffered saline (PBS), approx. pH 7.4; 0.2 μm filter sterilized

Purification :

Purified by precipitation and chromatography

Isotype :

Mouse IgG1

Storage :

Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.

Gene Full Name :

phosphate regulating endopeptidase homolog X-linked

Synonyms :

Phosphate-regulating neutral endopeptidase PHEX; Metalloendopeptidase homolog PEX; Vitamin D-resistant hypophosphatemic rickets protein; X-linked hypophosphatemia protein; HYP; PHEX; PEX

Protein Function :

Peptidase that cleaves SIBLING (small integrin-binding ligand, N-linked glycoprotein)-derived ASARM peptides, thus regulating their biological activity. Cleaves ASARM peptides between Ser and Glu or Asp residues. Regulates osteogenic cell differentiation and bone mineralization through the cleavage of the MEPE-derived ASARM peptide. Promotes dentin mineralization and renal phosphate reabsorption by cleaving DMP1- and MEPE-derived ASARM peptides. Inhibits the cleavage of MEPE by CTSB/cathepsin B thus preventing MEPE degradation.

Subcellular Localization :

Cell membrane. Single-pass type II membrane protein.

Tissue Specificity :

Specifically expressed in ovary. Expressed at low levels in kidney.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).

Background :

Phosphate-regulating neutral endopeptidase, X-linked also known as phosphate-regulating gene with homologies to endopeptidases on the X chromosome or metalloendopeptidase homolog PEX is an enzyme that in humans is encoded by the PHEX gene. It is mapped to Xp22.11. The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants.