Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 | Boster M00084-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348

catalog :

M00084-2

quantity :

100 uL

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

RM348

The same clone is also sold as:

Invitrogen: MA5-33071

reactivity :

human

application :

western blot, immunohistochemistry

product information

SKU :

M00084-2

Product Name :

Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348

Size :

100 uL

Clonality :

Monoclonal

Clone Number :

RM348

Host :

Rabbit

Reactivity :

Human

Application(s) :

WB, IHC

Application Details :

Immunohistochemistry (IHC): 1:500-1:1000 dilution; Western Blot (WB): 1:1000-1:20000 dilution.

Description :

Boster Bio Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 catalog # M00084-2. Tested in IHC, WB applications. This antibody reacts with Human.

Concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

PTGS2

Uniprot ID :

P35354

Immunogen :

A peptide corresponding to the C-terminus of human COX-2.

Contents :

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Prostaglandin G/H synthase 2

Synonyms :

Prostaglandin G/H synthase 2; 1.14.99.1; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2; PTGS2; COX2;

Molecular Weight :

68996 MW

Protein Function :

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Subcellular Localization :

Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

Research Category :

Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Cholesterol Metabolism, Endocrine Metabolism, Heart Disease, Hormone Biosynthesis, Lipid And Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids / Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Pathways And Processes, Platelets, Signal Transduction, Signaling Pathway, Tumor Biomarkers