Anti-cleaved Caspase-9 CASP9 Rabbit Monoclonal Antibody | Boster M00080-2 product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-cleaved Caspase-9 CASP9 Rabbit Monoclonal Antibody

catalog :

M00080-2

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

FEE-3

reactivity :

human, mouse

application :

western blot, immunoprecipitation

product information

SKU :

M00080-2

Product Name :

Anti-cleaved Caspase-9 CASP9 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

FEE-3

Host :

Rabbit

Reactivity :

Human, Mouse

Application(s) :

IP, WB

Application Details :

WB 1:500-1:2000 .IP 1:50

Description :

Boster Bio Anti-cleaved Caspase-9 CASP9 Rabbit Monoclonal Antibody catalog # M00080-2. Tested in IP, WB applications. This antibody reacts with Human, Mouse.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CASP9

Uniprot ID :

P55211

Immunogen :

A synthesized peptide derived from human cleaved Caspase-9

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Caspase-9

Synonyms :

Caspase-9; CASP-9; 3.4.22.62; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; APAF-3; ICE-like apoptotic protease 6; ICE-LAP6; Caspase-9 subunit p35; Caspase-9 subunit p10; CASP9; MCH6;

Molecular Weight :

46281 MW

Protein Function :

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP).

Tissue Specificity :

Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.

Research Category :

Apoptosis, Apoptotic Markers, Cancer, Caspases Etc, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways And Processes