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product summary
company name :
Boster
product type :
antibody
product name :
Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody
catalog :
M00078
quantity :
100 µl
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
AGH-14
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
product information
SKU :
M00078
Product Name :
Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody
Size :
100 µl
Clonality :
Monoclonal
Clone Number :
AGH-14
Host :
Rabbit
Reactivity :
Human, Mouse
Application(s) :
IP, IF, IHC, ICC, WB
Application Details :
WB 1:500-1:2000 .IHC 1:50-1:200 .ICC/IF 1:50-1:200 .IP 1:50
Description :
Boster Bio Anti-Nrf2 NFE2L2 Rabbit Monoclonal Antibody catalog # M00078. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse.
Concentration :
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Gene Name :
NFE2L2
Uniprot ID :
Q16236
Immunogen :
A synthesized peptide derived from human Nrf2
Form :
Liquid
Contents :
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification :
Affinity-chromatography
Storage :
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name :
Nuclear factor erythroid 2-related factor 2
Synonyms :
Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2; NFE2L2; NRF2;
Molecular Weight :
67827 MW
Protein Function :
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
Subcellular Localization :
Cytoplasm, cytosol. Nucleus. Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents.
Tissue Specificity :
Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.
Research Category :
Cardiovascular, Cell Biology, Epigenetics and Nuclear Signaling, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Nucleotide Metabolism, Oxidative Stress, Pathways And Processes, Redox Metabolism, Transcription
company information
Boster
3942 B Valley Ave
Pleasanton, CA 94566
Pleasanton, CA 94566
boster@bosterbio.com
https://www.bosterbio.com925.485.4527
headquarters: USA
Premium Provider of Antibodies and ELISA Kits
questions and comments