Anti-CD44 / HCAM Std. Antibody | Boster M00052 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-CD44 / HCAM Std. Antibody

catalog :

M00052

quantity :

100 ug/vial

price :

299 USD

host :

mouse

conjugate :

nonconjugated

clone name :

SPM521

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:100; loading ...; fig s1b	Wang J, Xu S, Duan J, Yi L, Guo Y, Shi Y, et al. Invasion of white matter tracts by glioma stem cells is regulated by a NOTCH1-SOX2 positive-feedback loop. Nat Neurosci. 2019;22:91-105 pubmed publisher

product information

sku :

M00052

name :

Anti-CD44 / HCAM Std. Antibody

price :

299 USD

immunogen :

Stimulated human leukocytes

form :

Liquid

host :

Mouse

contents :

Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

clonality :

Mouse Monoclonal Antibody [Clone SPM521]

description :

Anti-CD44 / HCAM Std. Antibody

size :

100 ug/vial

reactivity :

Human; Monkey

applications :

Flow Cytometry; IF; IHC; WB

clone number :

Clone SPM521

gene full name :

CD44 antigen

gene name :

CD44

protein function :

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

subcellular localization :

Cell membrane; Single-pass type I membrane protein. Colocalizes with actin in membrane protrusions at wounding edges.

synonyms :

CD44 antigen;CDw44;Epican;Extracellular matrix receptor III;ECMR-III;GP90 lymphocyte homing/adhesion receptor;HUTCH-I;Heparan sulfate proteoglycan;Hermes antigen;Hyaluronate receptor;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;CD44;LHR, MDU2, MDU3, MIC4;

tissue specificity :

Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.

uniprot id :

P16070