Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody | Boster M00048 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

catalog :

M00048

quantity :

100 µl

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

DCB-3

The same clone is also sold as:

MyBioSource: MBS179060

reactivity :

human, rat

application :

western blot

product information

SKU :

M00048

Product Name :

Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody

Size :

100 µl

Clonality :

Monoclonal

Clone Number :

DCB-3

Host :

Rabbit

Reactivity :

Human, Rat

Application(s) :

Application Details :

WB 1:500-1:2000 .

Description :

Boster Bio Anti-Caspase-1 CASP1 Rabbit Monoclonal Antibody catalog # M00048. Tested in WB applications. This antibody reacts with Human, Rat.

Concentration :

Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Gene Name :

CASP1

Uniprot ID :

P29466

Immunogen :

A synthesized peptide derived from human Caspase-1

Form :

Liquid

Contents :

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Purification :

Affinity-chromatography

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Caspase-1

Synonyms :

Caspase-1; CASP-1; 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Caspase-1 subunit p20; Caspase-1 subunit p10; CASP1; IL1BC, IL1BCE;

Molecular Weight :

45159 MW

Protein Function :

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Subcellular Localization :

Cytoplasm

Tissue Specificity :

Expressed in larger amounts in spleen and lung. Detected in liver, heart, small intestine, colon, thymus, prostate, skeletal muscle, peripheral blood leukocytes, kidney and testis. No expression in the brain.

Research Category :

Apoptosis, Caspases Etc, Cell Biology, Intracellular