Anti-MyD88 Monoclonal Antibody [2E9C2] | Boster M00025-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-MyD88 Monoclonal Antibody [2E9C2]

catalog :

M00025-2

quantity :

0.1 mg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2E9C2

The same clone is also sold as:

OriGene: TA319687
Invitrogen: MA5-15762
Rockland Immunochemicals: 200-301-CW6
Abnova: MAB2745

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

product information

SKU :

M00025-2

Product Name :

Anti-MyD88 Monoclonal Antibody [2E9C2]

Size :

0.1 mg

Clonality :

Monoclonal

Clone Number :

2E9C2

Host :

Mouse

Reactivity :

Human, Mouse

Application(s) :

ELISA, WB, IHC, IF

Application Details :

MyD88 antibody can be used for detection of MyD88 by Western blot at 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL. Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Application Notes :

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Description :

Boster Bio Anti-MyD88 Monoclonal Antibody [2E9C2] catalog # M00025-2. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse.

Concentration :

1 mg/mL

Gene Name :

MYD88

Uniprot ID :

Q99836

Immunogen :

Mouse monoclonal MyD88 antibody was raised against a recombinant protein corresponding to amino acids 176 to 280 of human MyD88.

Form :

Liquid

Contents :

MyD88 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

Purification :

MyD88 Monoclonal Antibody is Protein A purified.

Isotype :

IgG2b

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

MAX network transcriptional repressor

Synonyms :

Max-binding protein MNT; Class D basic helix-loop-helix protein 3; bHLHd3; Myc antagonist MNT; Protein ROX; MNT; BHLHD3; ROX

Protein Function :

Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.

Subcellular Localization :

Nucleus.

Recommended Detection Systems :

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.

Background :

MNT (Max's Next Tango) is a Max-binding protein that is encoded by the MNT gene. It is mapped to 17p13.3. The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.