Anti-TG beta TGFB1 Monoclonal Antibody | Boster M00019-2 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-TG beta TGFB1 Monoclonal Antibody

catalog :

M00019-2

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4F9C10 / 1B11B7

reactivity :

human

application :

western blot, ELISA

product information

SKU :

M00019-2

Product Name :

Anti-TG beta TGFB1 Monoclonal Antibody

Size :

100 ul

Clonality :

Monoclonal

Clone Number :

4F9C10 / 1B11B7

Host :

Mouse

Reactivity :

Human

Application(s) :

WB, ELISA

Application Details :

WB 1:500-1:2000 ELISA 1:10000

Description :

Boster Bio Anti-TG beta TGFB1 Monoclonal Antibody catalog # M00019-2. Tested in ELISA, WB applications. This antibody reacts with Human.

Concentration :

1 mg/ml

Gene Name :

TGFB1

Uniprot ID :

P01137

Immunogen :

Purified recombinant fragment of TGFbeta1 expressed in E. Coli.

Form :

Liquid

Contents :

Ascitic fluid containing 0.03% sodium azide.

Purification :

Affinity purification

Isotype :

IgG

Storage :

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Gene Full Name :

Myocyte-specific enhancer factor 2C

Synonyms :

Myocyte-specific enhancer factor 2C ; Myocyte enhancer factor 2C

Protein Name :

Myocyte-specific enhancer factor 2C

Molecular Weight :

51221 MW

Protein Function :

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

Subcellular Localization :

Nucleus

Tissue Specificity :

Expressed in brain and skeletal muscle.