Human Chemerin/RARRES2 PicoKine® Quick ELISA Kit | Boster FEK1329 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Chemerin/RARRES2 PicoKine® Quick ELISA Kit

catalog :

FEK1329

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK1329

Product Name :

Human Chemerin/RARRES2 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Human Chemerin/RARRES2 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human Chemerin/RARRES2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20 pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

RARRES2

Uniprot ID :

Q99969

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: V17-S163

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

78 pg/ml - 5,000 pg/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Background :

Chemerin, also known as RARRES2 or TIG2, is a protein that in humans is encoded by the RARRES2 gene. It is mapped to 7q36.1. Chemerin is a potent chemoattractant specific for antigen-presenting cells that requires proteolytic activation and acts as a ligand for the G protein-coupled receptor CMKLR1(also known as ChemR23). It is a 14 kDa protein secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. Chemerin was found to stimulate chemotaxis of dendritic cells and macrophages to the site of inflammation. What’s more, the active protein has several roles, including that as an adipokine, and is truncated on both termini from the proprotein.