Human CD21/CR2 PicoKine® Quick ELISA Kit | Boster FEK1315 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human CD21/CR2 PicoKine® Quick ELISA Kit

catalog :

FEK1315

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK1315

Product Name :

Human CD21/CR2 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Human CD21/CR2 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human CR2 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 20pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CR2

Uniprot ID :

P20023

Immunogen :

Expression system for standard: CHO; Immunogen sequence: Ile21-71

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<20 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Complement receptor type 2

Synonyms :

Complement receptor type 2;Cr2;Complement C3d receptor;Epstein-Barr virus receptor;EBV receptor;CD21;CR2;C3DR;

Protein Name :

Complement receptor type 2

Molecular Weight :

112916 MW

Protein Function :

Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.

Subcellular Localization :

Membrane; Single-pass type I membrane protein.

Tissue Specificity :

Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.

Sequence Similarities :

Belongs to the receptors of complement activation (RCA) family.

Background :

Complement receptor type 2 (CR2), also known as C3DR or CD21, is a protein that in humans is encoded by the CR2 gene. It is mapped to 1q32.2. CR2 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. CR2 is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. CR2, together with CD19, CD81, and CD225, forms the B-cell coreceptor complex, which lowers the activation threshold of the B-cell antigen receptor. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9).