Rat RANK PicoKine® Quick ELISA Kit | Boster FEK1281 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat RANK PicoKine® Quick ELISA Kit

catalog :

FEK1281

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK1281

Product Name :

Rat RANK PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Rat RANK PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Rat Tnfrsf11a in cell culture supernatants and serum. Sensitivity: 10pg/ml. Introduction: Boster's PicoKine® Quick ELISA kits features the high sensitivity of PicoKine® ELISA kits and the significantly reduced assay run time. Now you can run the entire ELISA assay in less than 1.5 hours. Compared to regular Picokine ELISA kits, the following sections in the datasheet are different: 1. kit components; 2. preparation before experiment; 3. assay protocol

Reactivity :

Rat

Application :

ELISA

Gene Name :

Tnfrsf11a

Uniprot ID :

F1M8Z6

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Q30-P213

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants and serum

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Synonyms :

Protein Tnfrsf11a ;Tnfrsf11a ;

Protein Name :

Tumor necrosis factor receptor superfamily member 11A

Molecular Weight :

67607 MW

Background :

Receptor Activator of Nuclear Factor kappa B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is a recently described TNF receptor family member, and its ligand, RANKL, promote survival of dendritic cells and differentiation of osteoclasts. RANK contains 383 amino acids in its intracellular domain (residues 234-616), which contain three putative TRAF-binding domains (termed I, II, and III). RANK interacts with various TRAFs through distinct motifs and activates NF-kappaB via a novel TRAF6 interaction motif, which then activates NIK, thus leading to NF-kappaB activation, whereas RANK most likely activates JNK through a TRAF2-interacting region in RANK. The standard in this kit is recombinant human RANK with the sequence of Q29-G213 aa. It is a dipolymer which compose of two chains, and the molecular weight of each is 48kda.