Mouse CCL9/Mip 1 Gamma PicoKine® Quick ELISA Kit | Boster FEK1225 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse CCL9/Mip 1 Gamma PicoKine® Quick ELISA Kit

catalog :

FEK1225

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK1225

Product Name :

Mouse CCL9/Mip 1 Gamma PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Mouse CCL9/Mip 1 Gamma PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Mouse Ccl9 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1pg/ml.

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Ccl9

Uniprot ID :

P51670

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: Q22-Q122

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

7.8 pg/ml - 500 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 9

Synonyms :

C-C motif chemokine 9;CCF18;Macrophage inflammatory protein 1-gamma;MIP-1-gamma;Macrophage inflammatory protein-related protein 2;MRP-2;Small-inducible cytokine A9;CCL9 (29-101);CCL9 (30-101);CCL9 (31-101);Ccl9;Mrp2, Scya10, Scya9;

Protein Name :

C-C motif chemokine 9

Molecular Weight :

13871 MW

Protein Function :

Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain.

Background :

Chemokine (C-C motif) ligand 9 (CCL9), also called MIP-1 gamma and MRP-2, is a small cytokine belonging to the CC chemokine family. CCL9 which found around Peyer's patches is secreted by follicle-associated epithelium (FAE), and it can attract dendritic cells that possess the cell surface molecule CD11b and the chemokine receptor CCR1. CCL9 is constitutively expressed in macrophages and myeloid cells. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.