Rat MIP-1Alpha/CCL3 PicoKine® Quick ELISA Kit | Boster FEK1219 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Rat MIP-1Alpha/CCL3 PicoKine® Quick ELISA Kit

catalog :

FEK1219

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK1219

Product Name :

Rat MIP-1Alpha/CCL3 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Rat MIP-1Alpha/CCL3 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Rat Ccl3 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 1pg/ml.

Reactivity :

Rat

Application :

ELISA

Gene Name :

Ccl3

Uniprot ID :

P50229

Immunogen :

Expression system for standard: E.coli; Immunogen sequence: A24-A92

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

7.8 pg/ml - 500 pg/ml

Sensitivity :

<1 pg/ml

Sample Type :

cell culture supernatants, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

C-C motif chemokine 3

Synonyms :

C-C motif chemokine 3;Macrophage inflammatory protein 1-alpha;MIP-1-alpha;Small-inducible cytokine A3;Ccl3;Mip1a, Scya3;

Protein Name :

C-C motif chemokine 3

Molecular Weight :

10335 MW

Protein Function :

Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.

Subcellular Localization :

Secreted.

Background :

Macrophage inflammatory protein-1 alpha (MIP-1 alpha), also called CCL3, LD78. The cDNA for MIP-1 alpha predicts a mature peptide of 69 amino acids with a molecular mass of 7,889 daltons. LD78 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, wound healing and tumorigenesis. MIP-1 alpha is a chemokine that has pro-inflammatory and stem cell inhibitory activities in vitro. It constitutes an important second signal for mast cell degranulation in the conjunctiva in vivo and consequently for acute-phase disease.