Human IL-1 RL1 / ST2 PicoKine® Quick ELISA Kit | Boster FEK1116 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human IL-1 RL1 / ST2 PicoKine® Quick ELISA Kit

catalog :

FEK1116

quantity :

96 wells/kit, with removable strips.

price :

499 USD

more info or order :

Boster product webpage

citations: 1

Reference
Galeone A, Lessana A, Mascolo E, Di Serio F, Marraudino N, Laborde F, et al. Interleukin-1 receptor-related protein ST2 and mitral valve repair outcome in patients with chronic degenerative mitral regurgitation. Thorac Cardiovasc Surg. 2014;62:47-51 pubmed publisher

image

image 1 :

Human IL1RL1/ST2 PicoKine ELISA Kit standard curve

product information

SKU :

FEK1116

Product Name :

Human IL-1 RL1 / ST2 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Price :

499 USD

Description :

Human IL-1 RL1 / ST2 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human IL1RL1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. Introduction: Boster's PicoKine® Quick ELISA kits features the high sensitivity of PicoKine® ELISA kits and the significantly reduced assay run time. Now you can run the entire ELISA assay in less than 1.5 hours. Compared to regular Picokine ELISA kits, the following sections in the datasheet are different: 1. kit components; 2. preparation before experiment; 3. assay protocol

Reactivity :

Human

Application :

ELISA

Gene Name :

IL1RL1

Uniprot ID :

Q01638

Immunogen :

Expression system for standard: NS0; Immunogen sequence: K19-S328

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Interleukin-1 receptor-like 1

Synonyms :

Interleukin-1 receptor-like 1;Protein ST2;IL1RL1;DER4, ST2, T1;

Protein Name :

Interleukin-1 receptor-like 1

Molecular Weight :

63358 MW

Protein Function :

Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.

Subcellular Localization :

Isoform C: Cell membrane.

Tissue Specificity :

Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.

Sequence Similarities :

Belongs to the interleukin-1 receptor family.

Background :

Interleukin 1 receptor-like 1, also known as IL1RL1 or ST2, is a protein that in humans is encoded by the IL1RL1 gene. The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. TL1RL1 is necessary for endotoxin tolerance and, by inhibiting TLR responses, enhances Th2 responses. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.

more info or order :

Boster product webpage