Human Chitinase 3-Like 1/YKL-40 PicoKine® Quick ELISA Kit

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human Chitinase 3-Like 1/YKL-40 PicoKine® Quick ELISA Kit

catalog :

FEK0974

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK0974

Product Name :

Human Chitinase 3-Like 1/YKL-40 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Human Chitinase 3-Like 1/YKL-40 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human Chitinase 3-Like 1/YKL-40 in cell culture supernatants, serum, plasma (heparin, EDTA) and urine. Sensitivity: 10 pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CHI3L1

Uniprot ID :

P36222

Immunogen :

Expression system for standard: NS0; Immunogen sequence: Y22-T383

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

62.5 pg/ml - 4,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin, EDTA) and urine

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Background :

Chitinase-3-like protein 1, also called CHI3L1 or YKL-40 is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. This gene is mapped to 1q32.1. Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.