Mouse GDNF PicoKine® Quick ELISA Kit | Boster FEK0935 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Mouse GDNF PicoKine® Quick ELISA Kit

catalog :

FEK0935

quantity :

96 wells/kit, with removable strips.

price :

499 USD

more info or order :

Boster product webpage

citations: 1

Reference
Chen X, Li H, Cao K, Wei C, Jin X. [The transduction of neurotrophin-3/GDNF attenuates the SGNC damage in deaf mice]. Zhonghua Yi Xue Za Zhi. 2003;83:1517-20 pubmed

image

image 1 :

Mouse GDNF PicoKine ELISA Kit standard curve

product information

SKU :

FEK0935

Product Name :

Mouse GDNF PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Price :

499 USD

Description :

Mouse GDNF PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Mouse Gdnf in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. Introduction: Boster's PicoKine® Quick ELISA kits features the high sensitivity of PicoKine® ELISA kits and the significantly reduced assay run time. Now you can run the entire ELISA assay in less than 1.5 hours. Compared to regular Picokine ELISA kits, the following sections in the datasheet are different: 1. kit components; 2. preparation before experiment; 3. assay protocol

Reactivity :

Mouse

Application :

ELISA

Gene Name :

Gdnf

Uniprot ID :

P48540

Immunogen :

Expression system for standard: NS0; Immunogen sequence: S78-I211

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Glial cell line-derived neurotrophic factor

Synonyms :

Glial cell line-derived neurotrophic factor;mGDNF;Astrocyte-derived trophic factor;ATF;Gdnf;

Protein Name :

Glial cell line-derived neurotrophic factor

Molecular Weight :

23662 MW

Protein Function :

Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Subcellular Localization :

Secreted.

Tissue Specificity :

Expressed in both the central nervous system (CNS) and in non-CNS tissues. Expressed in a highly dynamic pattern in the anterior neuroectoderm during the early stages of neurogenesis between E7.5 and E10.5. Beginning at E10.5, expression begins in mesenchymal tissues of several organs including the digestive tract, kidney, testis, frontonasal mass, tooth primordium, tongue, mandible, whisker follicles, ear, eye, limb bud and in distinct regions of the brain. Also expressed in the heart, ileum, liver and muscle.

Background :

Glial cell line-derived neurotrophic factor (GDNF) is a glycosylated, disulfide-bonded homodimer that is a distantly related member of the transforming growth factor-beta superfamily.1 GDNF, is a potent neurotrophic factor that promotes the survival of dopaminergic neurones in cultures including embryonic neuronal cultures.2 GDNF, in addition to its potential role in the differentiation and survival of central nervous system neurons, has profound effects on kidney organogenesis and the development of the peripheral nervous system.3 GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.

more info or order :

Boster product webpage