Human GDF-15 PicoKine® Quick ELISA Kit | Boster FEK0767 product information

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human GDF-15 PicoKine® Quick ELISA Kit

catalog :

FEK0767

quantity :

96 wells/kit, with removable strips.

price :

499 USD

more info or order :

Boster product webpage

citations: 1

Reference
Zhao N, Yang J. [Expression of serum GDF15 and its clinical significance in multiple myeloma patients]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2014;39:270-5 pubmed publisher

image

image 1 :

Human GDF-15 PicoKine ELISA Kit standard curve

product information

SKU :

FEK0767

Product Name :

Human GDF-15 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Price :

499 USD

Description :

Human GDF-15 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human GDF15 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml. Introduction: Boster's PicoKine® Quick ELISA kits features the high sensitivity of PicoKine® ELISA kits and the significantly reduced assay run time. Now you can run the entire ELISA assay in less than 1.5 hours. Compared to regular Picokine ELISA kits, the following sections in the datasheet are different: 1. kit components; 2. preparation before experiment; 3. assay protocol

Reactivity :

Human

Application :

ELISA

Gene Name :

GDF15

Uniprot ID :

Q99988

Immunogen :

Expression system for standard: CHO; Immunogen sequence: A197-I308

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<10 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA)

Capture/Detection Antibodies :

polyclonal antibody from goat, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

Growth/differentiation factor 15

Synonyms :

Growth/differentiation factor 15;GDF-15;Macrophage inhibitory cytokine 1;MIC-1;NSAID-activated gene 1 protein;NAG-1;NSAID-regulated gene 1 protein;NRG-1;Placental TGF-beta;Placental bone morphogenetic protein;Prostate differentiation factor;GDF15;MIC1, PDF, PLAB, PTGFB;

Protein Name :

Growth/differentiation factor 15

Molecular Weight :

34140 MW

Subcellular Localization :

Secreted .

Tissue Specificity :

Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.

Sequence Similarities :

Belongs to the TGF-beta family.

Background :

GDF-15 (Growth differentiation factor 15),also known as TGF-PL, MIC-1, PDF, PLAB, and PTGFB, is a protein belonging to the transforming growth factor beta superfamily that has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. Using FISH, the MIC1 gene is mapped to 19p13.2-p13.1. Its expression in liver can be significantly up-regulated in during injury of organs such as liver, kidney, heart and lung. GDF15 showed increased expression and secretion during erythroblast maturation. GDF15 functions as an antiinflammatory cytokine by directly interfering with chemokine signaling and integrin activation.

more info or order :

Boster product webpage