Human TIMP3 PicoKine® Quick ELISA Kit | Boster FEK0523 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human TIMP3 PicoKine® Quick ELISA Kit

catalog :

FEK0523

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK0523

Product Name :

Human TIMP3 PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Human TIMP3 PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human TIMP3 in cell culture supernatants, serum, plasma (heparin , EDTA) and saliva. Sensitivity: 2pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CST3

Uniprot ID :

P35625

Immunogen :

Expression system for standard: NS0; Immunogen sequence: C24-P211

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

156 pg/ml - 10,000 pg/ml

Sensitivity :

<2 pg/ml

Sample Type :

cell culture supernatants, serum, plasma (heparin , EDTA) and saliva

Capture/Detection Antibodies :

monoclonal antibody from mouse, polyclonal antibody from goat

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

TIMP metallopeptidase inhibitor 3

Synonyms :

TIMP-3 HSMRK222; K222; K222TA2; metalloproteinase inhibitor 3; MIG-5 protein; Protein MIG-5; pseudoinflammatory); SFD; TIMP metallopeptidase inhibitor 3; TIMP3; TIMP-3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy; Tissue inhibitor of metalloproteinases 3

Protein Name :

Metalloproteinase inhibitor 3

Background :

The tissue inhibitors of metalloproteinases (TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy (SFD).

Research Category :

Atherosclerosis, Cardiovascular, Caspases Etc, Cell Biology, Cell Type Markers, Neural Stem Cells, Stem Cells, Tags & Cell Markers, Tumor Associated