Human BDNF PicoKine® Quick ELISA Kit | Boster FEK0307 product information

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product summary

company name :

Boster

product type :

ELISA/assay

product name :

Human BDNF PicoKine® Quick ELISA Kit

catalog :

FEK0307

quantity :

96 wells/kit, with removable strips.

product information

SKU :

FEK0307

Product Name :

Human BDNF PicoKine® Quick ELISA Kit

Size :

96 wells/kit, with removable strips.

Description :

Human BDNF PicoKine® Quick ELISA Kit (90 minutes, 96 Tests). Quantitate Human BDNF in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA, citrate). Sensitivity: 15pg/ml.

Reactivity :

Human

Application :

ELISA

Gene Name :

CST3

Uniprot ID :

P23560

Immunogen :

Expression system for standard: NS0; Immunogen sequence: H129-R247

Cross-reactivity :

There is no detectable cross-reactivity with other relevant proteins.

Assay Range :

31.2 pg/ml - 2,000 pg/ml

Sensitivity :

<15 pg/ml

Sample Type :

cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA, citrate)

Capture/Detection Antibodies :

monoclonal antibody from mouse, monoclonal antibody from mouse

Storage :

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Gene Full Name :

brain derived neurotrophic factor

Synonyms :

Brain-derived neurotrophic factor;BDNF;Abrineurin;BDNF;

Protein Name :

Brain-derived neurotrophic factor

Background :

Brain-derived neurotrophic factor (BDNF) is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. It is a secreted protein with the molecular weight of 27.8kDa, consisting of 247 amino acids. It is known to promote neuronal survival and differentiation. BDNF shares substantial amino acid sequence identity with nerve growth factor (NGF). BDNF and neurotrophin-3 (NT-3) are two recently cloned neurotrophic factors that are homologous to NGF. mRNA products of the BDNF and NT-3 genes are detected in the adult human brain, suggesting that these proteins are involved in the maintenance of the adult nervous system. BDNF and other neurotrophins are critically involved in long-term potentiation (LTP). BDNF-mediated LTP is induced postsynaptically. BDNF has trophic effects on serotonergic (5-HT) neurons in the central nervous system. BDNF has an essential maintenance function in the regulation of anxiety-related behavior and in food intake through central mediators in both the basal and fasted state. It plays a role in treating breathing disorders such as respiratory insufficiency after spinal injury. The mature form of BDNF is identical in all mammals examined, and the gene encoding human BDNF to chromosome 11, band p13.

Research Category :

Atherosclerosis, Cardiovascular, Caspases Etc, Cell Biology, Cell Type Markers, Neural Stem Cells, Stem Cells, Tags & Cell Markers, Tumor Associated