Anti-human CD33 Antibody Unconjugated, Flow Validated | Boster FC01508 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-human CD33 Antibody Unconjugated, Flow Validated

catalog :

FC01508

quantity :

100Âµg, 500Âµg

price :

130; 520 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

WM53

reactivity :

human

application :

flow cytometry

product information

sku :

FC01508

name :

Anti-human CD33 Antibody Unconjugated, Flow Validated

price :

130; 520 USD

form :

Liquid

host :

Mouse

contents :

PBS, pH7.2, 0.09% NaN3

purification :

Protein A purified

clonality :

Monoclonal

description :

Mouse Monoclonal Anti-human CD33 Unconjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

size :

100Âµg, 500Âµg

reactivity :

Human

applications :

Flow Cytometry

background :

CD33, also known as Siglec-3 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67), is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. CD33 binds sialic acids, therefore is a member of the SIGLEC family of lectins. By fluorescence in situ hybridization, CD33 is mapped to 19q13.3-q13.4.

clone number :

WM53

gene full name :

Myeloid cell surface antigen CD33

gene name :

CD33

isotype :

IgG1,k

protein function :

Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

protein name :

Myeloid cell surface antigen CD33

research category :

immunology cell type markers myeloid cells stem cells hematopoietic progenitors hematopoietic stem cells human lineage negative

storage :

4 . Do not freeze.

subcellular localization :

Cell membrane; Single-pass type I membrane protein.

synonyms :

Myeloid cell surface antigen CD33;Sialic acid-binding Ig-like lectin 3;Siglec-3;gp67;CD33;CD33;SIGLEC3;

tissue specificity :

Monocytic/myeloid lineage cells.

uniprot id :

P20138