Anti-human CD16 Monoclonal Antibody PE Conjugated, Flow Validated

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Boster

product type :

antibody

product name :

Anti-human CD16 Monoclonal Antibody PE Conjugated, Flow Validated

catalog :

FC01408-PE

quantity :

25 Tests, 100 Tests, 200 Tests

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

3G8

reactivity :

human

application :

flow cytometry

product information

sku :

FC01408-PE

status :

Enabled

name :

Anti-human CD16 Monoclonal Antibody PE Conjugated, Flow Validated

category name :

Primary Antibodies, Monoclonal Antibodies, Flow Cytometry Antibodies

gene name :

FCGR3A

price various sizes :

25 Tests / $89 100 Tests / $199 200 Tests / $319

clonality :

Monoclonal

clone number :

3G8

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

contents :

PBS, pH7.2, 0.09% NaN3 and 0.2% (w/v) BSA

description :

Monoclonal clone# G2 antibody for CD16/FCGR3A detection. Host: Mouse.Size: 25 Tests, 100 Tests, 200 Tests. Tested applications: Flow Cytometry. Reactive species: Human. CD16/FCGR3A information: Molecular Weight: 29089 MW; Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Secreted. Exists also as a soluble receptor; Tissue Specificity: Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

short description :

Mouse Monoclonal Anti-human CD16 PE Conjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

description1 :

Introduction . CD16 (3G8) binds to the 50-65 kDa transmembrane protein of IgG FcgammaRIII, an surface antigen commonly associated with human NK cells. Besides surface expression on NK cells, it is also expressed on activated monocytes, macrophages, on neutrophils and placental trophoblasts in humans. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). 3G8 is also useful in experiments related to immunohistochemical staining, immunoprecipitation, NK cell proliferation, blocking of phagocytosis and blocking of immunoglobulin binding tthrough FcgammaRIII. . This antibody is routinely tested by flow cytometric analysis. Flow cytometry and other applications were tested during antibody development by CapricoBio or are reported in the literature. Application Information . Each lot of this antibody has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 5ul of this product is sufficient for staining of 1 million cells in a 100ul staining volume or 100ul of whole blood. It is recommended that antibody reactivity be empirically titrated for optimal performance in the application of interest.

size :

25 Tests, 100 Tests, 200 Tests

uniprot id :

P08637

host :

Mouse

immunogen :

Human peripheral blood T lymphocytes

form :

Liquid

purification :

Protein A purified

storage :

4 C and protect from prolonged exposure to light. Do not freeze.

isotype :

IgG1,k

sensitivity :

5ul per sample

application details :

Flow Cytometry, 5ul is enough to stain 1 million PBMCs or 100ul whole blood sample.

applications :

Flow Cytometry

reactivity :

Human

image labels :

Anti-human CD16 PE Conjugated, Flow Validated

research category :

Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Nk Cells, Stem Cells

synonyms :

Low affinity immunoglobulin gamma Fc region receptor III-A;CD16a antigen;Fc-gamma RIII-alpha;Fc-gamma RIII;Fc-gamma RIIIa;FcRIII;FcRIIIa;FcR-10;IgG Fc receptor III-2;CD16a;FCGR3A;CD16A, FCG3, FCGR3, IGFR3;

gene full name :

Low affinity immunoglobulin gamma Fc region receptor III-A

molecular weight :

29089 MW

protein function :

Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

subcellular localization :

Cell membrane ; Single-pass type I membrane protein . Secreted. Exists also as a soluble receptor.

tissue specificity :

Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

protein name :

Low affinity immunoglobulin gamma Fc region receptor III-A

last modified :

2/6/19 22:57