Anti-human CD5 Monoclonal Antibody Biotin Conjugated, Flow Validated | Boster FC00480-Biotin product information

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product summary

company name :

Boster

product type :

antibody

product name :

Anti-human CD5 Monoclonal Antibody Biotin Conjugated, Flow Validated

catalog :

FC00480-Biotin

quantity :

100Âµg

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

OKT1

reactivity :

human

application :

flow cytometry

product information

sku :

FC00480-Biotin

status :

Enabled

name :

Anti-human CD5 Monoclonal Antibody Biotin Conjugated, Flow Validated

category name :

Primary Antibodies, Monoclonal Antibodies, Flow Cytometry Antibodies

gene name :

CD5

price various sizes :

100ug / $158

clonality :

Monoclonal

clone number :

OKT1

concentration :

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

conjugate :

Biotin

contents :

PBS, pH7.2, 0.09% NaN3

description :

Monoclonal clone# G2 antibody for CD5 detection. Host: Mouse.Size: 100Âµg. Tested applications: Flow Cytometry. Reactive species: Human. CD5 information: Molecular Weight: 54578 MW; Subcellular Localization: Cell membrane; Single-pass type I membrane protein.

short description :

Mouse Monoclonal Anti-human CD5 Biotin Conjugated, designed for Flow Cytometry and validated by Flow Cytometry using Human cells.

description1 :

Introduction . The clone OKT-1 (CD5) is a 67 kDa protein and a member of the scavenger receptor cysteine-rich protein superfamily (SRCR). It is expressed on T lymphocytes, thymocytes, and IgM-secreting B cells (B-1 cells). . This antibody is routinely tested by flow cytometric analysis. Flow cytometry and other applications were tested during antibody development by CapricoBio or are reported in the literature. Application Information . Each lot of this antibody has been quality control tested by flow cytometric analysis of human PBMCs. For flow cytometric staining, the recommended dose of this antibody is 0.5ug per 1x106 cells in 100ul of staining volume followed by a fluorescent conjugated streptavidin (SA-PE). It is strongly suggested that the antibody reactivity be empirically titrated for optimal performance in the application of interest.

size :

100Âµg

uniprot id :

P06127

host :

Mouse

form :

Liquid

purification :

Protein A purified

storage :

4 C . Do not freeze.

isotype :

IgG1, k

sensitivity :

5ul per sample

application details :

User need to optimize the dilution ratio for this antibody

applications :

Flow Cytometry

reactivity :

Human

image labels :

Lymphocyte gated PBMCs stained with biotin conjugated anti-human clone OKT-1 (CD5) followed by SA-PE (red histogram). PBMCâ€™s lymphocytes stained with only SA-PE (Blue

background :

CD5, also known as T1 or LEU1, is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. It is mapped to 11q12.2. Although CD5 can be found on both T cells and B cells, T cells express higher levels of CD5 than B cells. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed. CD5 is upregulated on T cells upon strong activation. In the thymus, there is a correlation with CD5 expression and strength of the interaction of the T cell towards self-peptides. Nevertheless, CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli(such as bacterial proteins) and not by normal tissue proteins.

competitor equivalent skus :

sc 53204 sc 6986 sc 53054 sc 59085 sc 18912 sc 53206 sc 1180 sc 6985 sc 18898 sc 53205 sc 20920 sc 393087 sc 393019

research category :

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage

synonyms :

T-cell surface glycoprotein CD5;Lymphocyte antigen T1/Leu-1;CD5;CD5;LEU1;

gene full name :

T-cell surface glycoprotein CD5

molecular weight :

54578 MW

protein function :

May act as a receptor in regulating T-cell proliferation.

subcellular localization :

Cell membrane; Single-pass type I membrane protein.

protein name :

T-cell surface glycoprotein CD5

last modified :

2/6/19 22:57